李子婧/Zijing Li

        

李子婧,女,博士,副研究员

2009年7月毕业于北京师范大学化学学院,取得化学专业学士学位。同年进入北京师范大学刘伯里院士课题组攻读博士学位,钻研开发放射性核素标记的用于阿尔茨海默病早期、准确、无创诊断的Aβ斑块显像剂。2012年获得国家留学基金委公派留学资格到纽约大学医学院Center for Biomedical Imaging作为联合培养博士生交流16个月。2014年7月毕业于北京师范大学并获得博士学位。现主要从事分子影像放射性探针的设计、合成、标记以及体内外评价等工作。

通信地址:厦门市翔安区翔安南路厦门大学公共卫生学院曾宪梓楼138

邮编:361102

电话/传真:0592-2880646

电子邮箱: bnulzj@gmail.com

发表文章

Selected Publications

[1] Yajing Liu, Yanping Yang, Mingjian Sun, Mengchao Cui, Ying Fu, Yu Lin, Zijing Li*, Liming Nie*. Highly specific noninvasive photoacoustic and positron emission tomography of brain plaque with functionalized croconium dye labeled by a radiotracer. Chem. Sci., 2017. DOI: 10.1039/c6sc04798j.

[2] Hua Li, Deliang Zhang, Mengna Gao, Lumei Huang, Longguang Tang, Zijing Li,* Xiaoyuan Shawn Chen, Xianzhong Zhang*. Highly Specific C-C Bond Cleavage Induced FRET Fluorescence for in vivo Biological Nitric Oxide Imaging. Chem. Sci., 2017, 8, 2199-2203.

[3] Zijing Li*, Xuran Zhang, Xiaoyang Zhang, Mengchao Cui, Jie Lu, Xiaodong Pan*, Xianzhong Zhang*. 18F-Labeled Benzyldiamine Derivatives as Novel Flexible Probes for Positron Emission Tomography of Cerebral β-Amyloid Plaques. J. Med. Chem., 2016, 59, 10577−10585.

[4] Xiaolian Sun, Yesen Li, Ting Liu, Zijing Li, Xianzhong Zhang, Xiaoyuan Chen. Peptide-based imaging agents for cancer detection. Adv. Drug. Deliv. Rev., 2016. Accepted Manuscript. DOI: 10.1016/j.addr.2016.06.007.

[5] Xiaowei Wu, Linyi You, Deliang Zhang, Mengna Gao, Zijing Li, Duo Xu, Pu Zhang, Lumei Huang, Rongqiang Zhuang, Hua Wu, Xianzhong Zhang*. Synthesis and preliminary evaluation of a 18F-labeled ethisterone derivative [18F]EAEF for progesterone receptor targeting. Chem. Biol. Drug. Des., 2016, 1-7.

[6] Zijing Li, Mengchao Cui, Jinming Zhang, Jiapei Dai, Xiaojun Zhang, Peng Chen, Hongmei Jia, Boli Liu*. Novel 18F-labeled dibenzylideneacetone derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques. Eur. J. Med. Chem., 84(2014)628-638.

[7] Zijing Li, Mengchao Cui, Jiapei Dai, Xuedan Wang, Pingrong Yu, Yanping Yang, Jianhua Jia, Hualong Fu, Masahiro Ono, Hongmei Jia, Hideo Saji, and Boli Liu. Novel Cyclopentadienyl Tricarbonyl Complexes of 99mTc Mimicking Chalcone as Potential Single-Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Brain. J. Med. Chem., 56(2013)471-482.

[8] Zi-Jing Li, Hui-Ying Ren, Meng-Chao Cui, Winnie Deuther-Conrad, Rui-Kun Tang, Jörg Steinbach, Peter Brust, Bo-Li Liu, Hong-Mei Jia*, Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging. Bioorgan. Med. Chem., 19(2011)2911-2917.

发明专利

[1]一类与Aβ斑块具有高亲和力的新型小分子化合物及其合成和应用。发明人:崔孟超,刘伯里,李子婧。专利号:200910090109.8。
 

厦门大学分子影像暨转化医学研究中心 福建省分子影像诊疗工程技术研究中心 厦门市分子影像工程技术研究中心 版权所有
地址:福建省厦门市翔安区翔安南路厦门大学曾辉楼,邮编:361102
电话:0592-2880646,邮箱:xiamen-cmitm@xmu.edu.cn