张帆/Fan Zhang

张帆, 女, 医学博士, 副教授
 新疆医科大学基础医学硕士(2002);  首都医科大学影像医学及核医学博士(2007), 导师为首都医科大学宣武医院李坤诚教授; 2007-2010, 南京军区南京总医院医学影像科卢光明教授课题组博士后; 2010-2013,美国国立卫生院(NIH)生物医学与生物影像工程研究所(NIBIB)陈小元(Shawn Chen)教授课题组博士后。作为项目负责人承担2008中国博士后基金和江苏省博士后基金各一项, 2013国家自然科学青年基金一项和2014年国家自然科学基金面上项目一项。作为主要实验者参与国家自然科学基金重点项目和国家自然科学基金国际重大合作项目的研究。
Dr. Zhang received her M.D degree 2007 from the capital university of medical science. From 2010 to 2013, Dr. Zhang joined the Laboratory for Molecular Imaging and Nanomedicine (LOMIN) at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) as a postdoctoral visiting fellow under the supervision of Dr. Shawn Chen. Dr. Zhang’s research is mainly focused on multimodality molecular imaging of tumor and Neurological disorders.
研究方向:肿瘤和神经系统疾病的磁共振成像分子成像研究
研究成果:
2015
Fan Zhang*, Jianbo Cao, Xiao Chen, Kai Yang, Lei Zhu, Guifeng Fu, Xinglu Huang, Xiaoyuan Chen. Noninvasive Dynamic Imaging of Tumor Early Response to Nanoparticle-mediated Photothermal Therapy. Theranostics, accepted
Guo N, Zhang F, Zhang X, Guo J, Lang L, Kiesewetter DO, Niu G, Li Q, Chen X.Quantitative Evaluation of Tumor Early Response to a Vascular-Disrupting Agent with Dynamic PET. Mol Imaging Biol. 2015 Apr 21, 1-9.
2014
Huang X, Zhang F(co-first author), Wang Y, Sun X, Choi KY, Liu D, Choi JS, Shin TH, Cheon J, Niu G, Chen X. Design considerations of iron-based nanoclusters for noninvasive tracking of mesenchymal stem cell homing. ACS Nano. 2014 May 27;8(5):4403-14.
Huang X, Zhang F, Sun X, Choi KY, Niu G, Zhang G, Guo J, Lee S, Chen X. The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development. Biomaterials. 2014 Jan;35(2):856-65.
Chuang YJ, Zhen Z, Zhang F, Liu F, Mishra JP, Tang W, Chen H, Huang X, Wang L, Chen X, Xie J, Pan Z.Photostimulable near-infrared persistent luminescent nanoprobes for ultrasensitive and longitudinal deep-tissue bio-imaging.Theranostics. 2014 Aug 24;4(11):1112-22.
Zhang L, Gao S, Zhang F, Yang K, Ma Q, Zhu L. Activatable hyaluronic acid nanoparticle as a theranostic agent for optical/photoacoustic image-guided photothermal therapy. ACS Nano. 2014 Dec 23;8(12):12250-8.

2013
Huang X, Zhang F, Zhu L, Choi KY, Guo N, Guo J, Tackett K, Anilkumar P, Liu G, Quan Q, Choi HS, Niu G, Sun YP, Lee S, Chen X. Effect of injection routes on the biodistribution, clearance, and tumor uptake of carbon dots. ACS Nano. 2013 Jul 23;7(7):5684-93.
Cai Y, Zhu L, Zhang F, Niu G, Lee S, Kimura S, Chen X. Non-Invasive Monitoring of Pulmonary Fibrosis by Targeting Matrix Metalloproteinases (MMPs).Mol Pharm. 2013 June 3; 10(6): 2237–2247
Huang X, Zhang F, Wang H, Niu G, Choi KY, Swierczewska M, Zhang G, Gao H, Wang Z, Zhu L, Choi HS, Lee S, Chen X. Biomaterials. Mesenchymal stem cell-based cell engineering with multifunctional mesoporous silica nanoparticles for tumor delivery.2013 Feb; 34 (7):1772-80.
2012
Fan Zhang, Xinglu Huang, Chunqi Qian, Lei Zhu, Naoki Hida, Gang Niu, Xiaoyuan Chen. SynergisticEnhancement of IronOxideNanoparticle and Gadolinium for Dual-Contrast MRI. Biochemical and Biophysical Research Communications. 2012 Sep;425(4): 886–891
Fan Zhang, Lei Zhu, Xinglu Huang, Guangmin Lu, Gang Niu, Xiaoyuan Chen. Differentiation of Reactive and Tumor Metastatic Lymph Nodes with Diffusion-weighted and SPIO Enhanced MRI. Mol Imaging Biol. 2013,15, Issue 1, 40-47
Fan Zhang, Xinglu Huang, Lei Zhu, Ning Guo, Gang Niu, Magdalena Swierczewska, Seulki Lee, Hong Xu, Y. Andrew Wang, Khalid A. Mohamedali, Michael G. Rosenblum, Guangming Lu, Xiaoyuan Chen. Noninvasive Monitoring of Orthotopic Glioblastoma Therapy Response using RGD-Conjugated Iron Oxide Nanoparticles.  Biomaterials. 2012 Jul;33(21):5414-22
Xinglu Huang, Fan Zhang (co-first author), Lee, Seulki, Gang Niu, Xiaoyuan Chen.  Long-term Multimodal Imaging of Tumor Draining Sentinel Lymph Nodes using Mesoporous Silica-based Nanoprobes. Biomaterials. 2012 Jun;33(17):4370-8.
2011
 Fan Zhang, Gang Niu, Xin lin, Orit Jacobson, Ying Ma, Yulong He, Guangming Lu, Xiaoyuan Chen. Imaging tumor-induced sentinel lymph node lymphangiogenesis with LyP-1 peptide.  Amino Acids. 2011 Jul 19. [Epub ahead of print]
Fan Zhang, Lei Zhu, Gang Liu, Guangming Lu, Gang Niu, Xiaoyuan Chen.    Multimodality imaging to assess tumor apoptosis to Chemotherapy. Theranostics 2011; 1:302-309
Zhu L, Zhang F, Ma Y, Liu G, Kim K, Fang X, Lee S, Chen X. Membrane type matrix metalloproteinases imaging Using a Novel Fluorescent Photoprobe. Molecular Pharmaceutics, DOI: 10.1021/mp2002297
Fan Zhang, Jin Xie, Gang Liu, Yu-long He, Guang-ming Lu, Xiao-yuan Chen. In vivo MRI tracking of cell invasion and migration in a rat glioma model. Mol Imaging Biol. 2011 Aug;13(4):695-701.
Fan Zhang, Guang-ming Lu,Chi-Shing Zee. Comparative study of the sensitivity of ADC value and T(2) relaxation time for early detection of Wallerian degeneration. Eur J Radiol. 2011 Jul;79(1):118-23
Fan Zhang, Gang Niu, Guang-ming Lu , Xiao-yuan Chen.  Preclinical Lymphatic  Imaging. Mol Imaging Biol. 2011 Aug;13(4):599-612
Xie J, Zhang F, Aronova M, Zhu L, Lin X, Quan Q, Liu G, Zhang G, Choi KY, Kim K, Sun X, Lee S, Sun S, Leapman R, Chen X. Manipulating the power of an additional phase: a flower-like Au-Fe3O4 optical nanosensor for imaging protease expressions in vivo. ACS Nano. 2011 Apr 26;5(4):304351 
Xing R, Zhang F, Xie J, Aronova M, Zhang G, Guo N, Huang X, Sun X, Liu G, Bryant LH, Bhirde A, Liang A, Hou Y, Leapman RD, Sun S, Chen X. Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI. Nanoscale. 2011 Dec;3(12):4943-5.
Liu G, Xie J, Zhang F, Wang Z, Luo K, Zhu L, Quan Q, Niu G, Lee S, Ai H, Chen X. N-Alkyl-PEI-functionalized iron oxide nanoclusters for efficient siRNA delivery. Small. 2011 Oct 4;7(19):27429
Zhu L, Xie J, Swierczewska M, Zhang F, Lin X, Fang X, Niu G, Lee S, Chen X. Dual-functional, receptor-targeted fluorogenic probe for in vivo imaging of extracellular protease expressions. Bioconjug Chem. 2011 Jun 15;22(6):1001-5.
Zhu L, Xie J, Swierczewska M, Zhang F, Quan Q, Ma Y, Fang X, Kim K, Lee S, Chen X. Real-time video imaging of protease expression in vivo. Theranostics. 2011;1:18-27
Lin, Xin; Xie, Jin; Niu, Gang; Zhang, Fan; Gao, Haokao; Yang, Min; Quan, Qimeng; Aronova, Maria; Zhang, Guofeng; Lee, Seulki; Leapman, Richard; Chen, Xiaoyuan. Chimeric ferritin nanocages for multiple function loading and multimodal imaging. Nano Letters. 2011 Feb 9;11(2):814-9.
Quan Q, Xie J, Gao H, Yang M, Zhang F, Liu G, Lin X, Wang A, Eden HS, Lee S, Zhang G, Chen X. HSA coated iron oxide nanoparticles as drug delivery vehicles for cancer therapy. Mol Pharm. 2011 Oct 3;8(5):1669-76. Epub 2011 Aug 22.
 

厦门大学分子影像暨转化医学研究中心 福建省分子影像诊疗工程技术研究中心 厦门市分子影像工程技术研究中心 版权所有
地址:福建省厦门市翔安区翔安南路厦门大学曾辉楼,邮编:361102
电话:0592-2880646,邮箱:xiamen-cmitm@xmu.edu.cn