吴川六博士，男，1983年9月生，厦门大学化学化工学院教授，分子影像暨转化医学研究中心兼聘教授，博士生导师，固体表面物理化学国家重点实验室固定成员。分别于2005年和2010年获得厦门大学化学化工学院学士和博士学位。在攻读博士学位期间，于2008至2009年间在新加坡国立大学化学系交流学习一年。博士毕业后，获得瑞士苏黎世联邦理工学院ETH Fellowship资助，于2010至2012年间在该校化学与应用生物学系开展了两年的博士后研究。2012年12月份回国，成立独立课题组。2015年被聘为福建省“闽江学者”特聘教授。主要从事生命分析化学、分子影像探针等相关领域的课题研究。主要研究内容包括：1）发展高亲合力和高特异性的化学分子探针和高灵敏的荧光分析方法；2）发展具有限制构型的多元环肽分子模板，构建多功能的多肽分子成像探针工具；3）发展多肽分子内二硫键精准配对技术，构建多元环肽库，针对重要蛋白质分子，筛选活性多肽分子。目前，已在Nature Chem., J. Am. Chem. Soc., 以及Angew. Chem. Int. Ed.等国际知名杂志发表学术论文28篇（第一或通讯作者论文19篇）。
主要研究成果:
(1) Yunyang Ling,‡ Jing Ren,‡ Tao Li, Yibing Zhao and Chuanliu Wu*, POEGMA-Based Disulfide-Containing Fluorescent Probes for Imitating and Tracing Noninternalization-Based Intracellular Drug Delivery, Chem. Commun., 2016, 52, 4533−4536.
(2) Yiwu Zheng, Linxiang Zhai, Yibing Zhao, and Chuanliu Wu*, Orthogonal Cysteine-Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides, J. Am. Chem. Soc., 2015, 137, 15094−15097.
(3) Yujie Li,‡ Tao Li,‡ Jinghui Wang, Xiaojia Bao, Yibing Zhao, and Chuanliu Wu*, Multivalent Peptides Displayed on OEGMA-based Copolymers for the Modulation of Protein-Protein Interactions, Polym. Chem., 2015, 6, 7862−7870.
(4) Yaqi Chen,‡ Chaoqiong Yang,‡ Tao Li, Miao Zhang, Yang Liu, Marc A. Gauthier, Yibing Zhao, and Chuanliu Wu*, The Interplay of Disulfide Bonds, α-Helicity, and Hydrophobic Interactions Leads to Ultrahigh Proteolytic Stability of Peptides, Biomacromolecules, 2015, 16, 2347−2355.
(5) Linxiang Zhai, Jingjing Liang, Xiangqun Guo, Yibing Zhao, and Chuanliu Wu*, Extraordinary Modulation of Disulfide Redox-Responsiveness by Cooperativity of Twin-Disulfide Bonds, Chem. Eur. J., 2014, 20, 17507−17514.
(6) Chuanliu Wu, Jean-Christophe Leroux,* and Marc A. Gauthier*, Twin Disulfides for Orthogonal Disulfide Pairing and the Directed Folding of Multicyclic Peptides, Nature Chem., 2012, 4, 1044−1049.
(7) Chuanliu Wu, Cristina Belenda, Jean-Christophe Leroux, and Marc A. Gauthier*, Interplay of Chemical Microenvironment and Redox Environment on Thiol–Disulfide Exchange Kinetics, Chem. Eur. J., 2011, 17, 10064−10070.
(8) Chuanliu Wu, Jinqing Hong, Xiangqun Guo, Chaobiao Huang, Jinping Lai, Jinsheng Zheng, Jianbin Chen, Xue Mu, and Yibing Zhao*, Fluorescent Core-Shell Silica Nanoparticles as Tunable Precursors: towards Encoding and Multifunctional Nano-probes, Chem. Commun., 2008, 750−752.
(9) Chuanliu Wu, Chen Chen, Jinping Lai, Jianbin Chen, Xue Mu, Jinsheng Zheng, and Zhao, Yibing*, Molecule-Scale Controlled-Release System based on Light-Responsive Silica Nanoparticles, Chem. Commun., 2008, 2662−2664.
(10) Chuanliu Wu, Jinsheng Zheng, Chaobiao Huang, Jinping Lai, Shuyan Li, Chen Chen, and Yibing Zhao*, Hybrid Silica-Nanocrystal-Organic Dye Superstructures as Post-Encoding Fluorescent Probes, Angew. Chem. Int. Ed., 2007, 46, 5393−5396.